Prototype is a rather interesting game. It's a bit frenzied some times and hard to see what your character is doing while simultaneously fighting civilians, infected, monsters, and soldiers (tanks, APC's, choppers, guys with guns and AT).
The ability to pick up and use guns, hijack APCs, run up walls, morph into different people, etc makes it rather fun.
Transformers 2 on the other hand sucked. The keyboard/mouse controls are the worse. Most actions are Mouse 2 (which for me is a wheel button) and the combos call for using L-Shift and L-Ctrl at the same time which is near impossible while using WASD to move around.